Yes, you can use a Bose speaker with a Bluetooth device. Most Bose speakers have Bluetooth connectivity, which allows you to connect your device wirelessly to the speaker and play music or other audio through it. To connect a Bose speaker to a Bluetooth device, you will need to put the speaker into pairing mode and then search for it on your device. Once the two are paired, you will be able to stream audio from your device to the speaker.