Yes, Bose speakers can be used with Alexa or Google Home. Some Bose speakers, such as the Bose Home Speaker 500, have built-in support for Alexa and can be controlled using voice commands. Other Bose speakers, such as the SoundTouch series, can be connected to an Alexa or Google Home device using Bluetooth or an audio cable, allowing you to control the speaker using voice commands through the smart assistant. You can also use the Bose Music app to set up and control your Bose speakers with Alexa or Google Assistant.